[68] Yibo Zhou*, Jun Zhang, Shuanghong Sun, Weiju Chen, Yuping Wang, Huiqiu Shi, Ronghua Yang*, and Zhihe Qing*. Amplified Biosensors Powered by Endogenous Molecules for Intracellular Fluorescence Imaging, Analytical Chemistry, 2024.
[67] Yanmei Lu, Jiayue Liu, Yufang Hu*, Wenjun Dong, Caizhao Cheng, Zhihe Qing*, Shun Zhang*, Visual and quantitative determination of KAT Tip60 activity in circulating tumor cells using a smartphone, Sensors and Actuators B: Chemical,2024.
[66] Jiayue Liu, Yanmei Lu, Yufang Hu*, Qingqing Zhang, Sui Wang, Zhiyong Guo*, and Zhihe Qing*. Portable Detection of Lysine Acetyltransferase Activity in Lung Cancer Cells Based on a Miniature Electrochemical Sensor, Analytical Chemistry, 2024, 96, 14, 5546–5553.
[65] Yibo Zhou*, Shan Hu, Hong-Wen Liu, Xinyue Xiao, Weiju Chen, Sheng Yang, Huiqiu Shi, Zhengxuan Gu, Junbin Li, Ronghua Yang*, and Zhihe Qing*. Activity-Independent Enzyme-Powered Amplification for Improving Signal Stability and Fidelity in Biosensing, Chem. Biomed. Imaging 2024, 2, 4, 304–312.
[64] Ke Quan, Xiaoyuan Li, Jiaqi Deng, Weiju Chen, Zhen Zou, Kun Chen, Linlin Wu, Juewen Liu*, Zhihe Qing*. Pt-Decorated Gold Nanoflares for High-Fidelity Phototheranostics: Reducing Side-Effects and Enhancing Cytotoxicity toward Target Cells, Angew. Chem. Int. Ed. 2024, e202402881.
[63] Yanli Lei, Chuangchuang Li, Xinyue Ji, Haiyan Sun, Xiaowen Liu, Zenghui Mao, Weiju Chen, Zhihe Qing*, Juewen Liu. Lowering Entropic Barriers in Triplex DNA Switches Facilitating Biomedical Applications at Physiological pH, Angew. Chem. Int. Ed. 2024, e202402123.
[62] Junbin Li, Lifei Song, Weiguo Hu, Qin Zuo, Roumei Li, Min Dai, Yibo Zhou, and Zhihe Qing*. A Reversible Fluorescent Probe for In Situ Monitoring Redox Imbalance during Mitophagy，Analytical Chemistry, 2023, 95, 36, 13668–13673.
[61] Jingxuan Zhu, Qiaozhen Ye, Shuai Xu*, Haixia Li, Junbin Li* and Hongwen Liu*, β-galactosidase activatable chemiluminescent probe for in vivo imaging and point-of care test, Sensors and Actuators: B. Chemical, 396 (2023) 134521.
[60] Ke Quan, Jiajie Tong, Lifang Chen, Shuyao Fang, Mengjiao Li, Linlin Wu, Zhihe Qing*, Freezing-directed construction of enzyme/nano interfaces: Reagent less conjugation, superior activity and better stability, Chinese Chemical Letters 35 (2024) 108894.
[59] Yibo Zhou, Xiaofei Ma, Shan Hu, Sheng Yang, Jingru Guo, Junbin Li, Yue-Fei Zhang, Juewen Liu, Zhihe Qing*, and Ronghua Yang.* Rigidity-Dependent Emission: Inspired Selection of an ATP-Specific Polyvalent Hydrogen Binding-Lighted Fluorophore for Intracellular Amplified Imaging, Analytical Chemistry, 2023, 95, 21, 8318–8324.
[58] Taoyun Wang, Xu Huang, Sheng Yang, Shan Hu, Xianglan Zheng, Guojiang Mao, Yi Li*, Yibo Zhou.* Monitoring H2S fluctuation during autophagic fusion of lysosomes and mitochondria using a lysosome-targeting fluorogenic probe, Analytica Chimica Acta, 2023, 1265, 341356.
[57] Huihong Liu, Xianqing Zeng, Honghui Yin, Jing Chen, Wenzhi Xie, Guoqiang Zhou, Guojiang Mao, Yibo Zhou,* Sheng Yang.* A pH-switchable azo-based fluorescence reporter for lysosome-confined visualization of hypoxia status. Sensors & Actuators: B. Chemical., 2023, 381, 133431.
[56] Junbin Li, Na Wang, Mengyi Xiong*, Min Dai, Cheng Xie, Qianqian Wang, Ke Quan, Yibo Zhou*, and Zhihe Qing*. A Reaction-Based Ratiometric Bioluminescent Platform for Point-of-Care and Quantitative Detection Using a Smartphone, Analytical Chemistry，2023, 95, 18, 7142–7149.
[55] Junbin Li, Ying Zhou, Lifei Song, Sheng Yang, Qianqian Wang, Yibo Zhou, Xiaobing Zhang, Zhihe Qing*, Ronghua Yang*. A brain-targeted near-infrared nanobeacon for in situ monitoring H2S fluctuation during epileptic seizures. Analytical Chemistry, 2022，94，15085-15092.
[54] 马小飞，胡山，李俊彬，杨盛，谌委菊，卿志和，周怡波，杨荣华。细胞内源性分子辅助荧光信号放大策略及细胞成像，高等学校化学学报，2022，43（12），20220320.
[53] Qi Luo, Lingfeng Qin, Peng Zhang, Bo Feng, Xiaosheng Ye, Taiping Qing*, Zhihe Qing*, A persistent luminescent nanobeacon for practical detection of lead ions via avoiding background interference, Analytica Chimica Acta, 2022, 1198, 339555.
[52] Yibo Zhou, Zhengxuan Gu, Changhui Liu, Sheng Yang*, Xiaofei Ma, Qiaoshu Chen, Yanli Lei, Ke Quan, Juewen Liu, Zhihe Qing*, Ronghua Yang*. A Polymeric Nanobeacon for Monitoring the Fluctuation of Hydrogen Polysulfides During Fertilization and Embryonic Development. Angew. Chem. Int. Ed. 2022, e202114504.
[51] Jiaqi Deng, Jingyuan Xu, Minzhi Ouyang, Zhen Zou, Yanli Lei, Junbin Li, Zhihe Qing*, Ronghua Yang*. Target-triggered hairpin-free chain-branching growth of DNA dendrimers for contrast-enhanced imaging in living cells by avoiding signal dispersion. Chinese Chemical Letters, 2022, 33(2), 773-777.
[50] Guang‑Wei Fu, Guo‑Yan Luo, Xiao‑Xuan Li, Zhen Zou, Yan‑Li Lei, Zhi‑He Qing*, Jue‑Wen Liu, Rong‑Hua Yang.Detachment-Independent Cationic-Dipeptide Beacons: Reduced False-Negative Signal and Accelerated Fluorescent Lighting in Cell Imaging. J. Anal. Test. (2022). https://doi.org/10.1007/s41664-021-00207-7
[49] Lihua Zhang, Minzhi Ouyang, Yufei Zhang, Leiyi Zhang, Ziyun Huang, Libei He, Yanli Lei, Zhen Zou, Feng Feng and Ronghua Yang .The fluorescence imaging and precise suppression of bacterial infections in chronic wounds by porphyrin-based metal–organic framework nanorods, Materials Chemistry B, 2021, 9(38): 8048-8055.
[48] Yu Xizi, Lie Xiang, Sheng Yang*, Shuanglin Qu, Xianqing Zeng, Yibo Zhou, and Ronghua Yang*. A near-infrared fluorogenic probe with fast response for detecting sodium dithionite in living cells, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 245(1): 118887.
[47] Xiao Liu, Xiangyang Gong, Jie Yuan, Xiaopeng Fan, Xingxing Zhang, Tianbing Ren, Sheng Yang*, Ronghua Yang, Lin Yuan*, and Xiao-Bing Zhang. Dual-Stimulus Responsive Near-Infrared Reversible Ratiometric Fluorescent and Photoacoustic Probe for In Vivo Tumor Imaging, Analytical Chemistry, 2021, 93(13): 5420−5429.
[46] Shiya Chen, Mingjian Chen, Jinfeng Yang, Xianqing Zeng, Yibo Zhou, Sheng Yang*. Design and Engineering of Hypoxia and Acidic pH Dual-Stimuli-Responsive Intelligent Fluorescent Nanoprobe for Precise Tumor Imaging, Small, 2021, 93, 3726−3732.
[45] Zhen Zou, Libei He, Xiangxi Deng, Huangxiang Wang, Ziyun Huang, Qian Xue, Zhihe Qing*, Yanli Lei, Ronghua Yang*, and Juewen Liu. Zn2+-Coordination-Driven RNAAssembly with Retained Integrity and Biological Functions. Angew. Chem. Int. Ed. 2021, 60, 22970– 22976.
[44] Lifang Chen, Shuohui Xing, Yanli Lei, Qiaoshu Chen, Zhen Zou, Ke Quan, Zhihe Qing*, Juewen Liu, and Ronghua Yang*. A Glucose-Powered Activatable Nanozyme Breaking pH and H2O2 Limitations for Treating Diabetic Infections. Angew. Chem. Int. Ed. 2021, 60, 23534 –23539.
[43] Fengzhou Xu, Taiping Qing, Zhihe Qing*. DNA-coded metal nano-fluorophores: Preparation, properties and applications in biosensing and bioimaging. Nano Today, 2021, 36, 101021-101042.
[42] Yibo Zhou, Keyi Yin, Hao Dong, Sheng Yang,* JunBin Li, Jinqiu Luo, Yi Li, and Ronghua Yang.* Long-Lasting Bioluminescence Imaging of the Fibroblast Activation Protein by an Amphiphilic Block Copolymer-Based Probe. Analytical Chemistry, 2021, 93, 8, 3726-3732.
[41] Yibo Zhou,* Hao Dong, Zhengxuan Gu, Sheng Yang, Minzhi Ouyang, Zhihe Qing, Xiaofei Ma, Shan Hu, JunBin Li, and Ronghua Yang.* Self-Immolative Dye-Doped Polymeric Probe for Precisely Imaging Hydroxyl Radicals by Avoiding Leakage. Analytical Chemistry, 2021, 93, 8, 12944−12953.
[40] Yanli Lei, Jinlu Tang, Xiaoxiao He, Hui Shi,*Yu Zeng, Haiyan Sun, and Kemin Wang*. In Situ Modulating DNAzyme Activity and Internalization Behavior with Acid-Initiated Reconfigurable DNA Nanodevice for Activatable Theranostic. Analytical Chemistry, 2021, 93, 5629-5634.
[39] Lihua Zhang, Zhen Zou, Yanli Lei,* Zhihe Qing, c Yu Zeng,c Haiyan Sun, Feng Feng* and Ronghua Yang. Bidirectional modulation of microRNA with a clamp-like triplex switch for enhanced and programmed gene therapy. Chemical Communications, 2021, 57, 12131-12134.
[38] Ke Quan, Jiaoli Wang, Jing Li, Kemin Wang, Jin Huang.* An endogenous miRNA-initiated hybridization chain reaction and subsequent DNAzyme activation for cellular theranostics.CCS Chemistry, 2021, 3, DOI: 10.31635/ccschem.021.202101418.
[37]Hua Yang, Yufei Zhang, Xuan Xu, Huanxiang Wang, Ziyun Huang, Ziling Luo, Xiangxi Deng, Qian Xue, Zhihe Qing, Zhen Zou*, Ronghua Yang*, Visualization of long noncoding RNA MEG3 in living cells by a triple-helix-powered 3D catcher. ACS Applied Bio Materials, 2020, 3(5): 2588-2596.
[36]Zhen Zou, Xiaodou Liao, Le Yang, Ziyun Huang, Hua Yang, Qi Yan, Yufei Zhang, Zhihe Qing, Lihua Zhang, Feng Feng, Ronghua Yang*, Human serum albumin-occupying-based fluorescence turn-on analysis of antiepileptic drug tiagabine hydrochloride. Analytical Chemistry, 2020, 92(5): 3555-3562.
[35]Zhen Zou, Ziling Luo, Xuan Xu, Sheng Yang, Zhihe Qing, Juewen Liu, Ronghua Yang*, Photoactivatable fluorescent probes for spatiotemporal-controlled biosensing and imaging. TrAC Trends in Analytical Chemistry, 2020, 125: 115811.
[34]Le Yang, Jin Zheng, Zhen Zou*, Haiyan Cai, Peng Qi, Zhihe Qing, Qi Yan, Liping Qiu, Weihong Tan, Ronghua Yang*, Human serum albumin as an intrinsic signal amplification amplifier for ultrasensitive assays of the prostate-specific antigen in human plasma. Chemical Communications, 2020, 56: 1843-1846.
[33] Jinqiu Luo, Jinfeng Yang, Guangjie Li, Sheng Yang*, Yibo Zhou, Jun-Bin Li, Ge Huang, Yibo Hu, Shuangfa Zou, Qinghai Zeng, and Ronghua Yang*. Noncovalently Caged Firefly Luciferins Enable Amplifiable Bioluminescence Sensing of Hyaluronidase-1 Activity In Vivo, ACS Sensors, 2020, 5(6): 1726−1733.
[32] Yang Sheng, Jiaxing Jiang, Anxin Zhou, Yibo Zhou, Wenling Ye, Dong-Sheng Cao, and Ronghua Yang*. Substrate-Photocaged Enzymatic Fluorogenic Probe Enabling Sequential Activation for Light-Controllable Monitoring of Intracellular Tyrosinase Activity, Analytical Chemistry, 2020, 92(10): 7194−7199.
[31] Zhihe Qing, Guoyan Luo, Shuohui Xing, Zhen Zou, Yanli Lei, Juewen Liu*, Ronghua Yang*. Pt-S Bond Mediated Nanoflares for High-Fidelity Intracellular Applications by Avoiding Thiol Cleavage. Angewandte Chemie International Edition. 2020, 59, 14044 -14048.
[30] Zhihe Qing*, Jinlei Hu, Jingyuan Xu, Zhen Zou, Yanli Lei, Taiping Qing, Ronghua Yang*. An intramolecular catalytic hairpin assembly on a DNA tetrahedron for mRNA imaging in living cells: improving reaction kinetics and signal stability. Chemical Science, 2020, 11, 1985-1990.
[29] Zhihe Qing*, Ailing Bai, Lifang Chen, Shuohui Xing, Zhen Zou, Yanli Lei, Junbin Li, Juewen Liu, and Ronghua Yang*. An Activatable Nano-Enzyme Reactor for Co-Enhanced Chemodynamic and Starving Therapy against Tumor Hypoxia and Antioxidant Defense System. CCS Chemistry. 2020, 2, 1217-1230. Accepted date: 2020-06-20
[28] Zhihe Qing*, Yacheng Li, Younan Li, Guoyan Luo, Jinlei Hu, Zhen Zou, Yanli Lei, Juewen Liu, Ronghua Yang*. Thiol-suppressed I2-etching of AuNRs: acetylcholinesterase-mediated colorimetric detection of organophosphorus pesticides. Microchimica Acta, 2020, 187, 497-506.
[27] Zixin Jiang, Bo Feng*, Jin Xu, Taiping Qing*, Peng Zhang, Zhihe Qing*. Graphene biosensors for bacterial and viral pathogens. Biosensors and Bioelectronics, 2020, 166, 112471.
[26] Yibo Zhou, Sheng Yang,* Jingru Guo, Hao Dong, Keyi Yin, Wei Tao Huang, and Ronghua Yang.* In Vivo Imaging of Hypoxia Associated with Inflammatory Bowel Disease by a Cytoplasmic Protein-Powered Fluorescence Cascade Amplifier. Analytical Chemistry, 2020, 92, 5787-5794.
[25] Jun Li, Ke Yi, Yanli Lei,* Zhihe Qing, Zhen Zou, Yuedong Zhang, Haiyan Sun and Ronghua Yang.* Al centre-powered graphitic nanozyme with high catalytic efficiency for pH-independent chemodynamic therapy of cancer. Chemical Communications, 2020, 56, 6285-6288.
[24] Zhen Zou, Hua Yang, Qi Yan, Peng Qi, Zhihe Qing, Jing Zheng, Xuan Xu, Lihua Zhang, Feng Feng, Ronghua Yang*, Synchronous screening of multiplexed biomarkers of Alzheimer's disease by a length-encoded aerolysin nanopore-integrated triple-helix molecular switch. Chemical Communications, 2019, 55: 6433-6436.
[23] Zhen Zou, Qi Yan, Sixin Ai, Peng Qi, Hua Yang, Yufei Zhang, Zhihe Qing, Lihua Zhang, Feng Feng, Ronghua Yang*, Real-time visualizing mitophagy-specific viscosity dynamic by mitochondria-anchored molecular rotor. Analytical Chemistry, 2019,91: 8574−8581.
[22] Yuan Li, Sheng Yang, Lei Guo, Yue Xiao, Jinqiu Luo, Yinhui Li, Man Shing Wong, and Ronghua Yang*. Differentiation of Intracellular Hyaluronidase Isoform by Degradable Nanoassembly Coupled with RNA-Binding Fluorescence Amplification, Analytical Chemistry, 2019, 91(10): 6887−6893.
[21] Zhihe Qing*, Jingyuan Xu, Jing Zheng, Lei He, Zhen Zou, Sheng Yang, Weihong Tan, Ronghua Yang*. In Situ Amplification-Based Imaging of RNA in Living Cells. Angewandte Chemie International Edition，2019, 58, 11574 -11585. Accepted date: 2019-02-01
[20] Zhihe Qing*, Ailing Bai, Shuohui Xing, Zhen Zou, Xiaoxiao He, Kemin Wang, Ronghua Yang*. Progress in biosensor based on DNA-templated copper nanoparticles, Biosensors and Bioelectronics, 2019,137, 96–109. Accepted date: 2019-05-06
[19] Younan Li, Guoyan Luo, Zhihe Qing*, Xiaoxuan Li, Zhen Zou, Ronghua Yang*. Colorimetric aminotriazole assay based on catalase deactivation-dependent longitudinal etching of gold nanorods. Microchimica Acta, 2019, 186, 565-571. Accepted date: 2019-07-06
[18] Yibo Zhou, Sheng Yang,* Yue Xiao, Zhen Zou, Zhihe Qing, Juewen Liu, and Ronghua Yang.* Cytoplasmic Protein-Powered In Situ Fluorescence Amplification for Intracellular Assay of Low-Abundance Analyte. Analytical Chemistry, 2019, 91, 15179-15186.
[17] Ke Quan, Jing Li, Jiaoli Wang, Nuli Xie, Qiaomei Wei, Jinlu Tang, Xiaohai Yang, Kemin Wang and Jin Huang.* Dual-microRNA-controlled double-amplified cascaded logic DNA circuits for accurate discrimination of cell subtypes. Chemical Science, 2019, 10, 1442-1449.
[16] Jingru Guo, Sheng Yang*, Chongchong Guo, Qinghai Zeng, Zhihe Qing, Zhong Cao, Jishan Li, and Ronghua Yang*. Molecular Engineering of α-Substituted Acrylate ester Template for Efficient Fluorescence Probe of Hydrogen Polysulfides, Analytical Chemistry, 2018, 90(1): 881−887.
[15] Sheng Yang, Chongchong Guo, Yuan Li, Jingru Guo, Jie Xiao, Zhihe Qing, Jiangsheng Li, and Ronghua Yang*. A Ratiometric Two-Photon Fluorescent Cysteine Probe with Well-Resolved Dual Emissions Based on Intramolecular Charge Transfer-Mediated Two-Photon-FRET Integration Mechanism, ACS Sensors, 2018, 3(11): 2415−2422.
[14] Sheng Yang, Xidan Wen, Xiaoguang Yang, Yuan Li, Chongchong Guo, Yibo Zhou, Heping Li, and Ronghua Yang*. Visualizing Endogenous Sulfur Dioxide Derivatives in Febrile Seizure-Induced Hippocampal Damage by a Two-Photon Energy Transfer Cassette, Analytical Chemistry, 2018, 90(24): 14514−14520.
[13] Yibo Zhou, Zhicheng Huang, Ronghua Yang, Juewen Liu.* Selection and Screening of DNA Aptamers for Inorganic Nanomaterials, Chemistry – A European Journal, 2018, 24, 2525-2532.
[12] Zhihe Qing*, Lixuan Zhu, Lina Hou, Zhen Zou, Sheng Yang & Ronghua Yang*. A dsDNA-lighted fluorophore for monitoring protein-ligand interaction through binding-mediated DNA protection. Science China Chemistry, 2018, 61(12): 1630-1636.
[11] Xiaoxuan Li, Zhihe Qing*, Younan Li, Zhen Zou, Sheng Yang, and Ronghua Yang*. Natural Peptide Probe Screened for High-Performance Fluorescent Sensing of Copper Ion: Especially Sensitivity, Rapidity, and Environment-Friendliness. ACS Omega 2019, 4, 793−800.
[10]Zhen Zou, Peng Qi, Zhihe Qing, Jing Zheng, Sheng Yang, Weiju Chen, Ronghua Yang*, Technologies for analysis of circulating tumour DNA: Progress and promise. Trends in Analytical Chemistry, 2017, 97(1): 36-49.
[9] Yibo Zhou, Xiufang Zhang, Sheng Yang,* Yuan Li, Zhihe Qing, Jing Zheng, Jishan Li, Ronghua Yang.* Ratiometric Visualization of NO/H2S Cross-Talk in Living Cells and Tissues Using a Nitroxyl-Responsive Two-Photon Fluorescence Probe, Analytical Chemistr, 2017, 89, 4587-4594.
[8] Yibo Zhou, Biwu Liu, Ronghua Yang, Juewen Liu.* Filling in the Gaps between Nanozymes and Enzymes: Challenges and Opportunities. Bioconjugate Chemistry, 2017, 28, 2903-2909.
[7] Lixuan Zhu, Zhihe Qing*, Lina Hou, Sheng Yang, Zhen Zou, Zhong Cao, and Ronghua Yang*. Direct Detection of Nucleic Acid with Minimizing Background and Improving Sensitivity Based on a Conformation-Discriminating Indicator. ACS Sens. 2017, 2, 1198−1204.
[6] Zhihe Qing*, Lixuan Zhu, Xiaoxuan Li, Sheng Yang, Zhen Zou, Jingru Guo, Zhong Cao, and Ronghua Yang*. A Target-Lighted dsDNA-Indicator for High-Performance Monitoring of Mercury Pollution and Its Antagonists Screening. Environmental Science and Technology. 2017, 51, 11884-11890.
[5] Xiaoguang Yang, Yibo Zhou, Xiufang Zhang, Sheng Yang*, Yun Chen, b Jingru Guo, Xiaoxuan Li, Zhihe Qing, Ronghua Yang*, et al A TP-FRET-Based Two-Photon Fluorescent Probe for Ratiometric Visualization of Endogenous Sulfur Dioxide Derivatives in Mitochondria of Living Cells and Tissues, Chemical Communications,2016, 52(67): 10289−10292.
[4] Changhui Liu，Weiju Chen，Zhihe Qing*，Jing Zheng，Yue Xiao，Sheng Yang，Lili Wang，Yinhui Li，Ronghua Yang*. In Vivo Lighted Fluorescence via Fenton Reaction: A New Approach for Imaging of Hydrogen Peroxide in Living Systems. Analytical Chemistry, 2016, 88, 3998−4003.
[3] Le Yang, Zhihe Qing*, Changhui Liu, Qiao Tang, Jishan Li, Sheng Yang, Jing Zheng, Ronghua Yang*, and Weihong Tan. Direct Fluorescent Detection of Blood Potassium by Ion-Selective Formation of Intermolecular G‑Quadruplex and Ligand Binding，Analytical Chemistry, 2016, 88, 9285−9292.
[2] Zhihe Qing*，Lixuan Zhu，Sheng Yang，Zhong Cao，Xiaoxiao He，Kemin Wang，Ronghua Yang*, In situ formation of fluorescent copper nanoparticles for ultrafastzero-background Cu2+ detection and its toxicides screening. Biosensors and Bioelectronics，2016，78, 471-476.
[1] Zhihe Qing, Lina Hou, Le Yang, Lixuan Zhu, Sheng Yang, Jing Zheng, Ronghua Yang*. A Reversible Nanolamp for Instantaneous Monitoring of Cyanide Based on an Elsner-like Reaction. Analytical Chemistry, 2016, 88, 9759−9765.
